On Deck Thermal Cycler - ODTC®

Fast, uniform results from a thermal cycler that fits easily onto your deck

The INHECO ODTC® delivers rapid, accurate, and cost-effective sample processing for every sample, every time.
Thermal cyclers have become an essential tool in genomics, molecular biology and biotechnology. They’re used for modifying and amplifying genetic material, including for PCR, and in NGS (Next Generation Sequencing). To earn a place in your automated deck, a thermal cycler needs to deliver rapid, reproducible results that are uniform across the entire sample range for the whole run, whilst taking up minimal deck space. Labs, assay owners and integrators choose the INHECO ODTC® because it delivers the best results and does everything they need.

FAST, UNIFORM, ACCURATE HEATING
Thanks to our patented Vapor Chamber Mount® (VCM®) technology the ODTC® delivers reliable results, superfast, every time. With near-instantaneous, precise heating and cooling and transition to plateau temperature, the VCM® also guarantees uniformity across the entire plate, including unequally filled plates or wells. The ODTC's® horizontal lid can be opened automatically at any point in a run, with negligible effect on temperature, ensuring problem-free 24/7 automated operations.

SMALL AND FLEXIBLE
The ODTC® takes up minimal space on your deck with a footprint on just two standard microplates (124 mm H x 157 mm W x 248 mm L). The ODTC® is available with different ventilation configurations for flexible positioning, you can place 4 ODTC’s® in a square with no issue or problem with ventilation.

EASY TO INTEGRATE
The ODTC® has a SiLA-compliant interface that integrates easily into automated workflows, and almost every deck, without modifications. It’s already in use by the world’s leading deck manufacturers and is easy to integrate with new decks. And whether you choose the 96-well or 384-well version, in standard size or taller XL size, it’s compatible with all standard PCR plates and lids.

UNRIVALLED CONFIGURATIONS
The ODTC® is available in multiple configurations – at 1st glance, the range of options can be confusing. The flexibility can be split into 3 distinct areas:
  • Well Plate Type
    We offer the ODTC® configured for either 96 well plates of 384 well plates
  • Plate Height
    We offer the ODTC® in standard size for standard/low profile plates and in XL size for deep well plates
  • Ventilation
    We offer 4 different ventilation directions – downwards, rearwards, left & right
The INHECO ODTC® can be configured using any or all of the different areas – a total of 16 different configurations are available to deliver class leading flexibility to satisfy requirements.

RELIABLE AND SUPPORTED
Every INHECO device is designed, engineered and made in Germany and undergoes rigorous quality control before delivery. It comes with a global two-year warranty and full customer service including remote support, diagnostic and servicing options that focusses on minimizing operational downtime.

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Technical Specifications ODTC®


ODTC® 96

General specifications
Dimensions (H x W x L) 124.3 mm x 156.5 mm x 248 m
Weight Approx. 7.5 kg
Plate ejection Automated plate ejection mechanism with exchangeable ejection bars
ODTC® device DC input 24 Vdc / 1200 W *1)
Protection class III (according DIN EN 61140)
EMV device class Group 1 / class A (industrial requirements)
PCR plates 96 and 384 well VCM® optimized for specific PCR plates (other PCR plate formats only on request)
Maximum volume during PCR 100µl/well for 96 well version
ODTC® lid Opens and closes by horizontal move and is heated to avoid condensation running temperature profiles with open ODTC® Lid possible
Lid pressure Automated adjustment of lid pressure for different disposable and sealing options
Thermal specifications
Temperature range +4 °C to +99 °C [+39 °F to +210 °F] *2)
Temperature accuracy ±0.30 K at +55 °C [+131 °F]
Temperature uniformity ±0.20 K at +55 °C [+131 °F]
±0.20 K at +72 °C [+162 °F]
±0.20 K at +95 °C [+203 °F]
Heating rate average (slope) Max. 4.4 K/sec
Cooling rate average (slope) Max. 2.2 K/sec
Adjustable heating & cooling rate From 0.1 K to 4.4 K/sec
Lid temperature Adjustable between ambient temperature
+5.0 K to +115 °C [+5.0 K to +239 °F]
Lid default temperature +110 °C [+230 °F]
 

ODTC® 96 XL

General specifications
Dimensions (H x W x L) 129.3 mm x 156.5 mm x 285.2 mm
Weight Approx. 7.5 kg
Plate ejection Automated plate ejection mechanism with exchangeable ejection bars
Device DC input 24 Vdc / 1200 W *1)
Protection class III (according DIN EN 61140)
EMV device class Group 1 / class A (industrial requirements)
PCR plates 96 and 384 well VCM® optimized for specific PCR plates (other PCR plate formats only on request)
Maximum volume during PCR 100 µl/well for 96 well version
Lid Opens and closes by horizontal move and is heated to avoid condensation running temperature profiles with open ODTC® Lid possible
Lid pressure Automated adjustment of lid pressure for different disposable and sealing options
Thermal specifications
Temperature range +4 °C to +99 °C [+39 °F to +210 °F] *2)
Temperature accuracy ±0.30 K at +55 °C [+131 °F]
Temperature uniformity ±0.20 K at +55 °C [+131 °F]
±0.20 K at +72 °C [+162 °F]
±0.20 K at +95 °C [+203 °F]
Heating rate average (slope) Max. 4.4 K/sec
Cooling rate average (slope) Max. 2.2 K/sec
Adjustable heating & cooling rate From 0.1 K to 4.4 K/sec
Lid temperature Adjustable between ambient temperature
+5.0 K to +115 °C [+5.0 K to +239 °F]
Lid default temperature +110 °C [+230 °F]
 

ODTC® 384

General specifications
Dimensions (H x W x L) 124.3 mm x 156.5 mm x 248 mm
Weight Approx. 7.5 kg
Plate ejection Automated plate ejection mechanism with exchangeable ejection bars
Device DC input 24 Vdc / 1200 W *1)
Protection class III (according DIN EN 61140)
EMV device class Group 1 / class A (industrial requirements)
PCR plates 96 and 384 well VCM® optimized for specific PCR plates (other PCR plate formats only on request)
Maximum volume during PCR 50µl/well for 384 well version
Lid Opens and closes by horizontal move and is heated to avoid condensation running temperature profiles with open ODTC® Lid possible
Lid pressure Automated adjustment of lid pressure for different disposable and sealing options
Thermal specifications
Temperature range +4 °C to +99°C [+39 °F to +210 °F] *2)
Temperature accuracy ±0.30 K at +55 °C [+131 °F]
Temperature uniformity ±0.20 K at +55 °C [+131 °F]
±0.20 K at +72 °C [+162 °F]
±0.20 K at +95 °C [+203 °F]
Heating rate average (slope) Max 5.0 K/sec
Cooling rate average (slope) Max. 2.2 K/sec
Adjustable heating & cooling rate From 0.1 K to 5.0 K/sec
Lid temperature Adjustable between ambient temperature
+5.0 K to +115 °C [+5.0 K to +239 °F]
Lid default temperature +115 °C [+239 °F]
 

ODTC® 384 XL

General specifications
Dimensions (H x W x L) 129.3 mm x 156.5 mm x 285.2 mm
Weight Approx. 7.5 kg
Plate ejection Automated plate ejection mechanism with exchangeable ejection bars
Device DC input 24 Vdc / 1200W *1)
Protection class III (Compliant with DIN EN 61140)
EMV device class Group 1 / class A (industrial requirements)
PCR plates 96 and 384 well VCM® optimized for specific PCR plates (other PCR plate formats only on request)
Maximum volume during PCR 50 µl/well for 384 well version
Lid Opens and closes by horizontal move and is heated to avoid condensation running temperature profiles with open ODTC® Lid possible
Lid pressure Automated adjustment of lid pressure for different disposable and sealing options
Thermal specifications
Temperature range +4°C to +99 °C [+39 °F to +210 °F] *2)
Temperature accuracy ±0.30 K at +55 °C [+131 °F]
Temperature uniformity ±0.20 K at +55 °C [+131 °F]
±0.20 K at +72 °C [+162 °F]
±0.20 K at +95 °C [+203 °F]
Heating rate average (slope) Max 5.0 K/sec
Cooling rate average (slope) Max. 2.2 K/sec
Adjustable heating & cooling rate From 0.1 K to 5.0 K/sec
Lid temperature Adjustable between ambient temperature
+5.0 K to +115 °C [+5.0 K to +239 °F]
Lid default temperature +115 °C [+239 °F]
 
Specifications - ODTC® Power & Control Unit (PCU)
Dimensions (WxDxH horizontally placed) 256.5 mm x 414.5 mm x 58 mm *3)
Interface SiLA, Ethernet (RJ45 connector)
Weight Approx. 5.5 kg
AC input 100-240 V / 50/60 Hz (1250 W)
DC output 24 Vdc / 1200W
Protection class I (according DIN EN 61140)
Fuses 2 x T12A / 250 V
Environmental Conditions - ODTC® and ODTC® Power & Control Unit (PCU)
Tolerable relative humidity:
Operation 30-80% *4)
Transportation and storage 30-80% *4)
Temperature:
Operation +15 °C to +32 °C [+59 °F to +90 °F]
Transportation and storage -10 °C to +60 °C [+14 °F to +140 °F]

1) ODTC® device shall only be powered by the ODTC® Power & Control Unit.
2) Operation of ODTC® below ambient temperature: The operation of the ODTC® below ambient temperature.
3) Note: The ODTC® Power & Control Unit can be positioned vertically or horizontally.
4) Condensate can prevent the ODTC® from operating properly and can damage the ODTC®.


ODTC® Accessories

Inheco INHECO OVT - ODTC® Verification Tool
Check your On Deck Thermal Cycler is working perfectly.

Read more

Why use a thermal cycler?

Labs use a thermal cycler (or thermocycler, PCR machine, DNA amplifier) to put samples though repeated cycles of two temperature extremes. It is frequently used to amplify segments of DNA using the polymerase chain reaction (PCR). Thermal cyclers are also used in laboratories to enable other temperature-sensitive reactions, including restriction enzyme digestion and rapid diagnostics.

It works by precisely raising and lowering the temperature of its thermal block. Samples (in tubes) sit in wells in the block and are heated and cooled by the block.

What to look for in a thermal cycler
For PCR and other uses, the thermal cycler must be able to deliver exactly the same changes in temperature for every sample in a run, and for every run.
  • Temperature uniformity – delivering identical temperature across the entire block, with identical results for samples in the middle or on the edge of the block, and throughout the run.
  • Temperature accuracy – ensuring accurate and stable, reproduceable temperatures for the duration of the run, and for every sample in the block.
  • Uniformity and accuracy during open-drawer operations – enabling pipetting and enzyme introductions whenever needed, with negligible effect.
  • Rapid uniform temperature change (ramp rates) – reaching required temperatures as rapidly as possible whilst maintaining temperature uniformity across the entire block.
  • Sample integrity and contaminant reduction – by enclosing and sealing the batch during the run.
  • Minimized start-up and boot times – combined with rapid ramp rates so laboratories can complete significantly more batches per day.
  • Small footprint – delivering the required performance while taking up as little space on deck as possible.
  • Flexible positioning – with few, if any, restrictions on placement due to the thermal cycler’s air venting or obstruction of the deck arm.

Use of the INHECO ODTC® thermal cycler

The ODTC® is used in the PCR process (polymerase chain reaction), to amplify a gene sequence in a sample. The amplification follows an exponential curve, so that after several temperature cycles several million replicates are present in the sample. This high number is required for various detection methods, as the sensors of the measurement/detection systems only respond when there is sufficient signal-to-noise rate.

The ODTC® is also used for NGS (Next Generation Sequencing). The reading of the gene segment, i.e., the sequence in which the base pairs (ATGC) occur, is carried out by the sequencer, but in order for this to be able to process the sample, it’s necessary to prepare (or enrich) a sample of the gene segment using PCR.

The ODTC® is ideal for gene analysis. As gene analysis is used in more diagnostic procedures as well as in research work it requires automation, and the ODTC® is optimized for use in highly automated environments.

Superior thermal management from INHECO ODTC®

The ODTC® delivers fast, predictable heating and cooling across every sample, thanks to innovative technology

Patented Vapor Chamber Mount (VCM®) thermal cycling technology
  • The VCM® is the first 3D heat pipe to be used as a super-conductive thermal cycler mount for PCR disposables.
  • An internal 3D Heat Pipe uses evaporation & condensation to transfer heat, almost at the speed of sound.
  • Peltier elements provide rapid heating and cooling, but when compared to other technologies, the VCM® distributes the applied temperature much more evenly and rapidly in the mount.
  • The Super-conductive mount ensures consistent results over all wells.
  • Superfast transition to the target plateau temperature for all wells allows a reduction of the plateau time and speeds up the whole PCR process.
  • Thermal performance is unaffected by ambient conditions in the lab or deck, or by opening and closing the lid.
Horizontal-opening heated lid
  • VCM® technology ensures the lid has negligible influence on thermal performance, allowing open-drawer operations, such as adding a chemical or taking an aliquot, during incubation.
  • The lid slides in and out of the device, so there are no restrictions on operation open or closed.
  • No change in height or depth or additional space needed to open the lid, and no risk of interfering with the robot arm.
  • Access to samples from every side of the ODTC®, so your ODTC® can be placed anywhere on deck.
  • Enables 24/7 automated operation without supervision.
  • Adds full flexibility and control to your heating options: Choose to turn off the heating from the block and just use the heater in the lid OR run a different temperature or different ramp up in the block and the lid.
Software
  • SiLA-compliant, API available, IoT-ready. The ODTC® is quick to connect, and ready for future developments in your lab.
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Email: techhotline@inheco.com
 
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